America’s Coolest Southern Towns
Greenville, South Carolina
Greenville is in the midst of a pretty cool moment, impressing visitors with a flourishing downtown and blocks chock-full of boutique hotels and trendy kitchens. Our choice stay is the design-forward Hotel Domestique, which marries rustic charm (hand-hewn beams and stone wall) and brilliantly bare-bones guestrooms. Between jaunts on the GHS Swamp Rabbit Trail—a once-abandoned railway line revived in 2010 and transformed into a 21-mile walking and biking route—it’s time to dine at Restaurant 17. Inspired by European bistros, the spot’s locally-sourced menu is a crowd pleaser with kale and peach salads, Southern-style ramen, dry aged pork chops, and hand cut truffle fries.